Residual Lesion Score (Observational Study)

The aim of this research is to study whether a scoring system called the Residual Lesion Score will predict how children with congenital heart disease do after cardiac surgery. We hope the scoring system will help doctors and nurses understand which parts of cardiac surgery may affect a child’s recovery after surgery. The score may help doctors and nurses take better care of infants at the time of cardiac surgery. The study began in the summer of 2015 and was completed at seventeen Pediatric Heart Network centers in the United States and Canada. 1149 patients across the centers were enrolled in this study. The study is now closed to enrollment, and data collection has been completed.

Who was in the study?

This study enrolled children less than one year old who were undergoing one of the following cardiac surgeries: (1) repair of complete common atrioventricular canal; (2) repair of Tetralogy of Fallot with pulmonary stenosis; (3) repair of arterial switch operation; (4) stage I Norwood procedure; or (5) repair of interrupted/hypoplastic arch or coarctation with VSD closure.

What happened in the study?

For each child who participated in this study, we recorded information about the child’s medical history, cardiac surgery and post-operative recovery, including the child’s echocardiograms (ultrasound examination of the heart) performed for his or her routine care around the time of surgery. We also contacted families one year after their child’s surgery to ask about any medical or surgical procedures that may have occurred after the child’s hospital discharge. 

What were the results of the study?

Results of this study are currently being analyzed. The PHN is grateful to all of the families who participated in this study.